Technical Note: CT calibration for proton treatment planning by cross‐calibration with proton CT data
نویسندگان
چکیده
Purpose This study explores the possibility of a new method for x-ray computed tomography (CT) calibration by means cross-calibration with proton CT (pCT) data. The proposed aims at more accurate conversion Hounsfield Units (HU) into stopping power ratio (SPR) relative to water be used in proton-therapy treatment planning. Methods X-ray scan was acquired on synthetic anthropomorphic phantom, composed different tissue equivalent materials (TEMs). A pCT apparatus instead adopted obtain reference three-dimensional distribution phantom’s SPR values. After rigid registration, artificially blurred same resolution pCT. Then scatter plot showing voxel-by-voxel values as function HU employed link two measurements and thus obtaining cross-calibrated curve. tested planning system then compared conventional based exactly TEMs constituting phantom. Results Cross-calibration provided an mapping, better than calibration. dose single beams optimized map recomputed CT, showing, respect calibration, minor deviation fall-off (lower 1%). Conclusions presented data demonstrated that, data, heterogeneous phantom can paving way use biological samples, their description patients’ tissues. overcomes limitations requiring homogenous only available TEMs, which fail accurately mimicking properties Once sample is its corresponding maps, procedure could other PT centers, even when not equipped system.
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ژورنال
عنوان ژورنال: Medical Physics
سال: 2021
ISSN: ['2473-4209', '1522-8541', '0094-2405']
DOI: https://doi.org/10.1002/mp.14698